Description
Ibutamoren (Ibutamoren, Ibutamorol, Nutrobal, Ibutamorol, laboratory code MK-677, MK-0677 or L-163,191) is a potent, non-peptide long-acting ghrelin receptor agonist that stimulates growth hormone secretion. Today it is one of the most powerful stimulators of the production of natural growth hormone and insulin-like growth factor (IGF-1).
The uniqueness of the drug lies in the fact that, by increasing the secretion of several hormones in the body, including growth hormone and IGF-1, it does not affect the level of cortisol, and also, by changing the metabolism of adipose tissue, it can effectively reduce it, which makes it indispensable for building high-quality muscle mass. Ibutamoren has the same effect on the body as growth hormone, but the cost is cheaper than artificial growth hormone and is safer.
How MK-677 Works MK-677 acts on several areas of the brain that are responsible for metabolic interaction. It does this in 4 ways:
– increases the production of the hormone GHRH (GHRH causes an increase in the secretion of the anterior pituitary somatotropic hormone),
– reduces the level of somatostatin (somatostatin is a peptide hormone that inhibits the secretion of growth hormone),
– promotes GHRH signals in the pituitary gland, limits somatostatin receptor signals.
The effect of the use of Ibutamoren
Studies of the effect of Ibutamoren on the human body have shown that a single dose of the drug at a dose of 25 mg induces an average peak concentration of GH equal to 22.1 μg / l. Higher dosages cause even higher levels of peak concentration of growth hormone. Ibutamoren maintains the plasma level of growth hormone, due to which it is produced by a smooth background. By increasing the level of growth hormone, Ibutamoren increases muscle mass, strength, and reduces the production of body fat. It also reduces muscle wastage, improves muscle strength and walking speed, especially among the elderly, and increases bone density.
Studies have shown that Ibutamoren improves the quality and duration of sleep, and improved sleep quality contributes to better health. Ibutamoren also enhances lipolysis, so it is used to treat obesity and complications associated with it. The use of the drug allows you to increase the level of IGF-1 by 39-89%. The impact of IGF-1 on the human body: Fat oxidation (fat burning). Increase in lean muscle mass. Wound healing. Restoration of damaged tendons, ligaments.
Athletes of various sports use Ibutamoren to increase endurance, performance, muscle mass and fat burning. The drug is familiar to professional bodybuilders and is rapidly gaining popularity among amateurs. The advantage of using the drug is that this drug:
The main effects of the use of Ibutamoren:
Studies have shown that the effect of the drug does not depend on gender, age and other indicators of a person.
A daily dose of 25 mg is comparable to injectable growth hormone. With a weight of up to 80 kg, take 1 capsule per day on an empty stomach at bedtime (if the evening intake of the drug interferes with sleep, then the intake should be postponed to the morning and taken before breakfast on an empty stomach).
If your weight is more than 80 kg, then you should add one more capsule before breakfast (total one capsule in the evening before bedtime, the second in the morning on an empty stomach). The duration of growth hormone stimulation after a single dose of the drug is 8 hours or more.This duration of growth hormone production is very effective in stimulating the production of insulin-like growth factor-1.
Do I need PCT (Post Cycle Therapy)?
MK-677 does not affect testosterone levels, so PCT is not needed.
Can women use Ibutamoren?
Ibutamoten is non-androgenic, so there is no risk of virilization and women can use it safely. Moreover, one of the first intended uses of MK-677 is in the treatment of women suffering from postmenopausal osteoporosis.
What SARMs and peptides does it combine with?
Ibutamoten has strong enough effects to be taken alone, however, it is possible to improve the results from the cycle when combined with SARMs or peptides. A list of the most popular bundles is given on this page in the Kits section. Our consultant will help you draw up an individual admission scheme.
How long will the result be visible?
With the right approach to the training process, rest, nutrition, the first results from the use of the drug will be visible by the end of the first week. MK-677 is quite powerful and results can be tangible.
Side effects from the use of Ibutamoren
The drug has no side effects. The performance of the drug is felt by such signs as numbness of the hands, fingers, lethargy, a slight increase in appetite, which are inherent in an increased level of growth hormone. Also, like growth hormone, another fairly rare side effect is water retention. However, this can be easily resolved with dietary adjustments, and those with experience may additionally use diuretics.
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